Cell Biology Antibodies 8
Anti-CLEC11A Antibody (CAB3634)
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- SKU:
- CAB3634
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-CLEC11A Antibody |
| Antibody SKU: | CAB3634 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549, Jurkat, 22Rv1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ARGA EREW EGGW GGAQ EEER EREA LMLK HLQE ALGL PAGR GDEN PAGT VEGK EDWE MEED QGEE EEEE ATPT PSSG PSPS PTPE DIVT YILG RLAG LDAG LHQL HVRL HALD TRVV ELTQ GLRQ LRNA AGDT RDAV QALQ EAQG RAER EHGR LEGC LKGL RLGH KCFL LSRD FEAQ AAAQ ARCT ARGG SLAQ PADR QQME ALTR YLRA ALAP YNWP VWLG VHDR RAEG LYLF ENGQ RVSF FAWH RSPR PELG AQPS ASPH PLSP DQPN GGTL ENCV AQAS DDGS WWDH DCQR RLYY VCEF PF |
| Gene ID: | 6320 |
| Uniprot: | Q9Y240 |
| Cellular Location: | Cytoplasm, Secreted |
| Calculated MW: | 35kDa |
| Observed MW: | 46kDa |
| Synonyms: | CLEC11A, CLECSF3, LSLCL, P47, SCGF |
| Background: | This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. |
| UniProt Protein Function: | CLEC11A: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: extracellular space; cytoplasm; extracellular region Molecular Function:growth factor activity; carbohydrate binding Biological Process: positive regulation of cell proliferation |
| UniProt Code: | Q9Y240 |
| NCBI GenInfo Identifier: | 34223087 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9Y240.1 |
| Molecular Weight: | |
| NCBI Full Name: | C-type lectin domain family 11 member A |
| UniProt Protein Name: | C-type lectin domain family 11 member A |
| UniProt Synonym Protein Names: | C-type lectin superfamily member 3; Lymphocyte secreted C-type lectin; Stem cell growth factor; p47 |
| UniProt Gene Name: | CLEC11A |
| UniProt Entry Name: | CLC11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CLEC11A antibody (CAB3634) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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