Developmental Biology
Anti-DLX2 Antibody (CAB8410)
- SKU:
- CAB8410
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-DLX2 Antibody |
| Antibody SKU: | CAB8410 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DLX2 (NP_004396.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DLX2 (NP_004396.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTGV FDSL VADM HSTQ IAAS STYH QHQQ PPSG GGAG PGGN SSSS SSLH KPQE SPTL PVST ATDS SYYT NQQH PAGG GGGG GSPY AHMG SYQY QASG LNNV PYSA KSSY DLGY TAAY TSYA PYGT SSSP ANNE PEKE DLEP |
| Gene ID: | 1746 |
| Uniprot: | Q07687 |
| Cellular Location: | Nucleus |
| Calculated MW: | 23kDa/34kDa |
| Observed MW: | 39kDa |
| Synonyms: | DLX2, TES-1, TES1 |
| Background: | Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. |
| UniProt Protein Function: | DLX2: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Belongs to the distal-less homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2q32 Molecular Function:protein binding; transcription factor activity Biological Process: brain development |
| NCBI Summary: | Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q07687 |
| NCBI GenInfo Identifier: | 2506529 |
| NCBI Gene ID: | 1746 |
| NCBI Accession: | Q07687.2 |
| UniProt Secondary Accession: | Q07687,B4DMK4, B7ZA14, |
| UniProt Related Accession: | Q07687 |
| Molecular Weight: | 23,021 Da |
| NCBI Full Name: | Homeobox protein DLX-2 |
| NCBI Synonym Full Names: | distal-less homeobox 2 |
| NCBI Official Symbol: | DLX2 |
| NCBI Official Synonym Symbols: | TES1; TES-1 |
| NCBI Protein Information: | homeobox protein DLX-2 |
| UniProt Protein Name: | Homeobox protein DLX-2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | DLX2 |
| UniProt Entry Name: | DLX2_HUMAN |
 | Western blot analysis of extracts of rat brain, using DLX2 antibody (CAB8410) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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