Immunology Antibodies 3
Anti-EXOC1 Antibody (CAB8749)
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- SKU:
- CAB8749
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-EXOC1 Antibody |
| Antibody SKU: | CAB8749 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RNFD KCIS NQIR QMEE VKIS KKSK VGIL PFVA EFEE FAGL AESI FKNA ERRG DLDK AYTK LIRG VFVN VEKV ANES QKTP RDVV MMEN FHHI FATL SRLK ISCL EAEK KEAK QKYT DHLQ SYVI YSLG QPLE KLNH FFEG VEAR VAQG IREE EVSY QLAF NKQE LRKV IKEY PGKE VKKG LDNL YKKV DKHL CEEE NLLQ VVWH SMQD EFIR QYKH FEGL IARC YPGS GVTM EFTI QDIL DYCS SIAQ SH |
| Gene ID: | 55763 |
| Uniprot: | Q9NV70 |
| Cellular Location: | |
| Calculated MW: | 100kDa/101kDa |
| Observed MW: | 102kDa |
| Synonyms: | EXOC1, BM-102, SEC3, SEC3L1, SEC3P |
| Background: | The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| UniProt Code: | Q9NV70 |
| NCBI GenInfo Identifier: | 67944634 |
| NCBI Gene ID: | 55763 |
| NCBI Accession: | NP_001020095.1 |
| UniProt Secondary Accession: | Q9NV70,Q8R3S6, |
| UniProt Related Accession: | Q9NV70 |
| Molecular Weight: | 100,283 Da |
| NCBI Full Name: | exocyst complex component 1 isoform 1 |
| NCBI Synonym Full Names: | exocyst complex component 1 |
| NCBI Official Symbol: | EXOC1 |
| NCBI Official Synonym Symbols: | SEC3; SEC3P; BM-102; SEC3L1 |
| NCBI Protein Information: | exocyst complex component 1; SEC3-like 1; exocyst complex component Sec3 |
| UniProt Protein Name: | Exocyst complex component 1 |
| UniProt Synonym Protein Names: | Exocyst complex component Sec3 |
| Protein Family: | Exocyst complex component |
| UniProt Gene Name: | EXOC1 |
| UniProt Entry Name: | EXOC1_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using EXOC1 Antibody (CAB8749) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Western blot analysis of extracts of mouse brain, using EXOC1 Antibody (CAB8749) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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