GenieFluor 488 Anti-Human IL-10 Antibody [JES3-9D7]

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SKU:
AGEL3154
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Human
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
JES3-9D7
Conjugation:
AF488

Description

Product Name:GenieFluor 488 Anti-Human IL-10 Antibody [JES3-9D7]
Product Code:AGEL3154
Clone No:JES3-9D7
Synonyms:Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF
Reactivity:Human
Host Species:Rat
Applications:ICFCM
Isotype:Rat IgG1, κ
Isotype Control:GenieFluor 488 Rat IgG2a, κ Isotype Control [2A3] (AGEL2650)
Conjugation:AF488
Form:Liquid
Fluorescent Label:AF488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID:3586
Swissprot:P22301
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.

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