Enzymes Recombinant Proteins

Human ADH6 Recombinant Protein (RPPB1357)

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SKU:
RPPB1357
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P28332
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human ADH6 Recombinant Protein
Product Code:RPPB1357
Size:20µg
Species:Human
Target:ADH6
Synonyms:Alcohol dehydrogenase 6, ADH6, ADH-5.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The ADH6 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 30% glycerol, 0.15M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMSTTGQ VIRCKAAILW KPGAPFSIEE VEVAPPKAKE VRIKVVATGL CGTEMKVLGS KHLDLLYPTI LGHEGAGIVE SIGEGVSTVK PGDKVITLFL PQCGECTSCL NSEGNFCIQF KQSKTQLMSD GTSRFTCKGK SIYHFGNTST FCEYTVIKEI SVAKIDAVAP LEKVCLISCG FSTGFGAAIN TAKVTPGSTC AVFGLGGVGL SVVMGCKAAG AARIIGVDVN KEKFKKAQEL GATECLNPQD LKKPIQEVLF DMTDAGIDFC FEAIGNLDVL AAALASCNES YGVCVVVGVL PASVQLKISG QLFFSGRSLK GSVFGGWKSR QHIPKLVADY MAEKLNLDPL ITHTLNLDKI NEAVELMKTG KCIRCILLL

Alcohol dehydrogenase 6 (ADH6) belongs to the alcohol dehydrogenase family. Alcohol dehydrogenase family members metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. ADH6 is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5� UTR, which is a steroid hormone receptor binding site.

ADH6 Human Recombinant produced E. coli is a single polypeptide chain containing 399 amino acids (1-375) and having a molecular mass of 42.4kDa.ADH6 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ADH6: class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]Protein type: Cofactor and Vitamin Metabolism - retinol; Amino Acid Metabolism - tyrosine; EC 1.1.1.1; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesisChromosomal Location of Human Ortholog: 4q23Cellular Component: cytosolMolecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependentBiological Process: ethanol oxidation; response to ethanol
UniProt Protein Details:
NCBI Summary:This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P28332
NCBI GenInfo Identifier:254763246
NCBI Gene ID:130
NCBI Accession:P28332.2
UniProt Secondary Accession:P28332,Q58F53, B3KS45
UniProt Related Accession:P28332
Molecular Weight:39,831 Da
NCBI Full Name:Alcohol dehydrogenase 6
NCBI Synonym Full Names:alcohol dehydrogenase 6 (class V)
NCBI Official Symbol:ADH6��
NCBI Official Synonym Symbols:ADH-5��
NCBI Protein Information:alcohol dehydrogenase 6
UniProt Protein Name:Alcohol dehydrogenase 6
UniProt Synonym Protein Names:
Protein Family:Alcohol dehydrogenase
UniProt Gene Name:ADH6��
UniProt Entry Name:ADH6_HUMAN
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