Cardiovascular Recombinant Proteins
Human ALK/ACVRL1 Recombinant Protein (RPES4895)
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- SKU:
- RPES4895
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cardiovascular
Description
system_update_altDatasheet
Human ALK/ACVRL1 Recombinant Protein
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.
| Product Name: | Human ALK/ACVRL1 Recombinant Protein (RPES4895) |
| Product Code: | RPES4895 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Serine/Threonine-Protein Kinase Receptor R3, SKR3, Activin Receptor-Like Kinase 1, ALK-1, TGF-B Superfamily Receptor Type I, TSR-I, ACVRL1, ACVRLK1, ALK1,HHT,HHT2,ORW2,SKR3 |
| Accession: | P37023 |
| Sequence: | Asp22-Gln118 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human ALK-1 is produced by our Mammalian expression system and the target gene encoding Asp22-Gln118 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 37.6 kDa |
| AP Mol Mass: | 50-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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