Cytokines Recombinant Proteins

Human APOL4 Recombinant Protein (RPPB5721)

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SKU:
RPPB5721
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BPW4
Research Area:
Cytokines

Description

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Product Name:Human APOL4 Recombinant Protein
Product Code:RPPB5721
Size:10µg
Species:Human
Target:APOL4
Synonyms:APOL-IV, APOLIV, Apolipoprotein L4, ApoL-IV.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:APOH protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 10% glycerol and 0.4M Urea.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMGSWVQL ITSVGVQQNH PGWTVAGQFQ EKKRFTEEVI EYFQKKVSPV HLKILLTSDE AWKRFVRVAE LPREEADALY EALKNLTPYV AIEDKDMQQK EQQFREWFLK EFPQIRWKIQ ESIERLRVIA NEIEKVHRGC VIANVVSGST GILSVIGVML APFTAGLSLS ITAAGVGLGI ASATAGIASS IVENTYTRSA ELTASRLTAT STDQLEALRD ILRDITPNVL SFALDFDEAT KMIANDVHTL RRSKATVGRP LIAWRYVPIN VVETLRTRGA PTRIVRKVAR NLGKATSGVL VVLDVVNLVQ DSLDLHKGAK SESAESLRQW AQELEENLNE LTHIHQSLKA G

Apolipoprotein L 4 (APOL4) belongs to the apolipoprotein L family. APOL4 plays a role in lipid exchange and transport through the body, in addition to reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. APOL4 is highly expressed in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis

APOH Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 371 amino acids (1-348 a.a.) and having a molecular mass of 41.1kDa.APOH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:APOL4: May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. Belongs to the apolipoprotein L family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; Lipid-binding; SecretedChromosomal Location of Human Ortholog: 22q11.2-q13.2Cellular Component: extracellular space; intracellular membrane-bound organelleDisease: Schizophrenia
UniProt Protein Details:
NCBI Summary:The protein encoded by this gene is a member of the apolipoprotein L family and may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. Only one of the isoforms appears to be a secreted protein. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BPW4
NCBI GenInfo Identifier:143811364
NCBI Gene ID:80832
NCBI Accession:Q9BPW4.3
UniProt Secondary Accession:Q9BPW4,Q9BQ37, Q9BXQ8
UniProt Related Accession:Q9BPW4
Molecular Weight:38,619 Da
NCBI Full Name:Apolipoprotein L4
NCBI Synonym Full Names:apolipoprotein L4
NCBI Official Symbol:APOL4��
NCBI Official Synonym Symbols:APOLIV; APOL-IV��
NCBI Protein Information:apolipoprotein L4
UniProt Protein Name:Apolipoprotein L4
UniProt Synonym Protein Names:Apolipoprotein L-IV; ApoL-IV
Protein Family:Apolipoprotein
UniProt Gene Name:APOL4��
UniProt Entry Name:APOL4_HUMAN
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