Autophagy Recombinant Proteins

Human ATG4A Recombinant Protein (RPES3144)

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SKU:
RPES3144
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Autophagy

Description

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Human ATG4A Recombinant Protein

Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.

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