Growth Factors & Cytokines Recombinant Proteins

Human CD40L/TNFSF5 Recombinant Protein (RPES5163)

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SKU:
RPES5163
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines

Description

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Human CD40L/TNFSF5 Recombinant Protein

CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein from the TNF superfamily. CD40LG exists as a trimer in membrane-bound and soluble form, both of which are bioactive. CD40L is a CD40 ligand that activates signal transduction in CD40LG-expressing cells through ligation. CD40LG is a differentiation antigen that T-cells express on their surface. It stimulates B-cell proliferation and production of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been found to generate and destroy tumour cells in peripheral blood monocytes. It also co-stimulates the proliferation of activated T-cells and this is accompanied by the production of IFN-gamma; TNF-alpha; and IL2. Human CD40L/TNFSF5 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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