Human CDKN2C / p18INK4c ELISA Kit

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SKU:
HUFI01690
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P42773
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
CDKN2C, Cyclin-dependent kinase 4 inhibitor C, p18-INK6, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, CDKN6, p18, CDK6 inhibitor p18, cyclin-dependent kinase inhibitor 2C, p18, inhibits CDK4
Reactivity:
Human
Research Area:
Cell Cycle

Description

Human CDKN2C / p18INK4c ELISA Kit

CDKN2C (Cyclin Dependent Kinase Inhibitor 2C) encodes a protein that is an inhibitor of cell division through mechanisms involving direct inhibition of the G1/S phase cyclin-dependent kinase, CDK4/6. Its expression is tightly regulated during development with high levels in fetal tissues and low or absent expression in adult tissues. Mutations in CDKN2C cause Rubinstein-Taybi syndrome 2, which features craniofacial defects, broad thumbs and halluces, developmental delay, growth retardation, heart defects, microcephaly, intellectual disability, seizures, obesity and pterygia. CDKN2C has also been associated with autism spectrum disorder, malignant rhabdoid tumor of the kidney, and lung cancers.

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