Human Cyclin D1 ELISA Kit

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SKU:
HUFI00736
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P24385
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
CCND1, BCL-1, PRAD1 oncogene, B-cell lymphoma 1 protein, BCL-1 oncogene, BCL1, PRAD1, Cyclin-D1, Cyl-1, cyclin D1, G1, S-specific cyclin D1, G1, S-specific cyclin-D1, PRAD1B-cell CLL, lymphoma 1
Reactivity:
Human
Research Area:
Cell Cycle

Description

Human Cyclin D1 ELISA Kit

Cyclin D1 acts as a regulator of CDK kinases during the cell cycle, and belongs to the highly conserved cyclin family. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Expression of Cyclin D1 is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in multiple myeloma and Von Hippel-Lindau syndrome.

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