Growth Factors & Cytokines Recombinant Proteins

Human DKK3 Recombinant Protein (RPES2330)

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SKU:
RPES2330
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines

Description

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Human DKK3 Recombinant Protein

Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. Dkk-3 also have one prokineticin domain. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.

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