Cardiovascular Recombinant Proteins

Human FGF-2/FGF basic/FGFb Recombinant Protein (RPES4411)

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SKU:
RPES4411
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cardiovascular

Description

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Human FGF-2/FGF basic/FGFb Recombinant Protein

Fibroblast growth factors (FGF) are a group of heparin-binding proteins produced by cells that promote cell proliferation and specialization in a variety of tissues. FGFs have a wide range of biological functions in both vivo and in vitro, including mitogenesis; cellular migration; differentiation; angiogenesis; and wound healing. In cell culture media, the cells of human embryonic stem cell (hESC) cultures require FGF basic (also known as bFGF) to remain undifferentiated and pluripotent. Thermostable FGF basic was engineered for enhanced stability in culture media; without modification of its biological function. FGF basic is a necessary component of stem cell culture media for keeping cells in an undifferentiated state. Because FGF basic is sensitive; frequent media changes are required. The thermostable FGF basic is a two-day media change option that requires no media changes over the weekend. The thermostable FGF basic was more stable than FGF basic in biochemistry tests; and it maintained cell growth, pluripotency, and differentiation potential with a two-day feeding regimen. Human FGF-2/FGF basic/FGFb Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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