Human GAD1 / Glutamate decarboxylase 1 ELISA Kit

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SKU:
HUFI01158
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q99259
Sensitivity:
0.938ng/ml
Range:
1.563-100ng/ml
ELISA Type:
Sandwich
Synonyms:
GAD1, Glutamate Decarboxylase 1, GAD67, GAD25, Glutamate decarboxylase 67 kDa isoform
Reactivity:
Human
Research Area:
Neuroscience

Description

Human GAD1 / Glutamate decarboxylase 1 ELISA Kit

GAD1/Glutamate decarboxylase 1 breaks down glutamic acid, a chemical that occurs naturally in the body. GAD1/Glutamate decarboxylase 1 is responsible for converting L-glutamic acid to gamma-aminobutyric acid. GAD1/Glutamate decarboxylase 1 has been associated with diabetic disease since it was found to be an autoantigen and autoreactive T cell target in insulin-dependent diabetes. Deficiency in GAD1/Glutamate decarboxylase 1 has been linked to pyridoxine dependency with seizures and stiff man syndrome. GAD1-related disorders include Developmental and Epileptic Encephalopathy 89, as well as Inherited Congenital Spastic Tetraplegia. Alanine and aspartate metabolism are two of GAD1 related processes, along with Synaptic Neurotransmission: GABAergic Inhibition.

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