Human HIF-1AN / HIF-1 alpha inhibitor ELISA Kit

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SKU:
HUFI00694
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9NWT6
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
HIF1AN, FIH-1, Hypoxia-inducible factor 1-alpha inhibitor, HIF-1AN, Peptide-aspartate beta-dioxygenase, Factor inhibiting HIF-1, FIH1, hypoxia inducible factor 1, alpha subunit inhibitor, Hypoxia-inducible factor asparagine hydroxylase
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human HIF-1AN / HIF-1 alpha inhibitor ELISA

HIF-1AN / HIF-1 alpha inhibitor is an orally bioavailable small molecule that exhibits specific inhibition of the transcriptional activity of HIF-1. HIF-1AN / HIF-1 alpha inhibitor has been shown to inhibit hypoxia induced increase in VEGF secretion, angiogenesis and cell proliferation by interfering with the function of HIF-1alpha. HIF-1AN / HIF-1 alpha inhibitor is ideal for targeting angiogenesis associated with diseases such as cancer or macular degeneration. Inhibition of HIF-1 for therapeutic purposes has also been tested in models of ischemic diseases and Alzheimer's disease.

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