Human PIN1 ELISA Kit

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SKU:
HUFI02016
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q13526
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich
Synonyms:
PIN1, dod, DOD, UBL5, peptidyl-prolyl cis, trans isomerase, NIMA-interacting, peptidylprolyl cis, trans isomerase, NIMA-interacting 1, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, prol
Reactivity:
Human
Research Area:
Cell Cycle

Description

Human PIN1 ELISA

Peptidyl-prolyl peptide bonds are isomerized by peptidyl-prolyl isomerase (PPIases) enzymes. PIN1 codes for one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to adjust the posttranslational modifications of its substrates. This PPIase's structural regulation has a major influence on key proteins in cell growth, genotoxic and other stress responses, the immune response, pluripotency induction and maintenance, germ cell development, neuronal differentiation, and survival. Frontotemporal dementia and alzheimer's disease are two diseases linked to PIN1. Regulation of TP53 activity and interferon-gamma signalling are among PIN1 associated pathways.

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