Human PLA2R1 Full-Length Bioactive Membrane Protein (HDFP127)

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SKU:
HDFP127
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q13018

Description

system_update_altDatasheet
Product nameHuman PLA2R1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP127
Product CategoryFull Length Transmembrane Proteins
Target:PLA2R1
Uniprot:Q13018
Description:Human PLA2R1 full length protein-synthetic nanodisc
Molecular Weight:The human full length PLA2R1 protein has a MW of 168.6 kDa
Protein Family:Druggable Genome, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Delivery:In Stock
UsageResearch use only
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