Human Thymidine Kinase 1 / TK1 ELISA Kit

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SKU:
HUFI01773
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P04183
Sensitivity:
0.0375pmol/L
Range:
0.06-4pmol/L
ELISA Type:
Sandwich
Synonyms:
TK1, thymidine kinase 1, soluble, thymidine kinase 1 soluble isoform, thymidine kinase, cytosolic, thymidine kinase-1, TK2
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human Thymidine Kinase 1 / TK1 ELISA Kit

Thymidine Kinase 1 / TK1 is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine, in the biosynthesis of dTTP which is required for DNA replication. Thymidine Kinase 1 / TK1 levels fluctuate depending on the cell cycle stage, and can act as a low activity dimer or a high activity tetramer. High levels of Thymidine Kinase 1 / TK1 have been used as a biomarker for diagnosing and categorizing many types of cancers. Diseases associated with Thymidine Kinase 1 / TK1 include Hypochondroplasia and Thanatophoric Dysplasia.

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