Human TLR9 Full-Length Bioactive Membrane Protein (HDFP126)

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SKU:
HDFP126
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9NR96

Description

system_update_altDatasheet
Product nameHuman TLR9 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP126
Product CategoryFull Length Transmembrane Proteins
Target:TLR9
Uniprot:Q9NR96
Description:Human TLR9 full length protein-synthetic nanodisc
Molecular Weight:The human full length TLR9 protein has a MW of 115.9 kDa
Protein Family:Druggable Genome, Transmembrane
Protein Pathways:Toll-like receptor signaling pathway
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CD289
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Delivery:In Stock
UsageResearch use only
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