Human WT1 / Wilms Tumor Protein ELISA Kit

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SKU:
HUFI01056
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P19544
Sensitivity:
9.375pg/ml
Range:
15.625-1000pg/ml
ELISA Type:
Sandwich
Synonyms:
WT1, Wilms tumor protein, GUD, WAGR, WIT-2, WT33, AWT1, NPHS4GUD, WAGR, Wilms tumor 1
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human WT1 / Wilms Tumor Protein ELISA Kit

WT1 is a transcription factor with four zinc-finger motifs at the C-terminus and a DNA-binding domain rich in proline and glutamine at the N-terminus. WT1 is mutated in a subset of Wilms tumour patients and plays an important role in the normal development of the urogenital system. WT1 has a complex tissue-specific and polymorphic imprinting pattern, with maternal and paternal alleles expressing biallelic and monoallelic expression in different tissues. Wilms Tumor 1 and Frasier Syndrome are two diseases linked to WT1. Regulation of Telomerase, Embryonic and Induced Pluripotent Stem Cells, and Lineage-specific Markers are some of the pathways linked to WT1.

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