Enzymes Recombinant Proteins

Mouse CTSZ Recombinant Protein (RPPB5808)

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SKU:
RPPB5808
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q9WUU7
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse CTSZ Recombinant Protein
Product Code:RPPB5808
Size:10µg
Species:Mouse
Target:CTSZ
Synonyms:CathepsinZ, CTSZ.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered clear solution.
Formulation:CTSZ protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greaterthan 95% as determined by SDS-PAGE.
Amino Acid Sequence:ARARLYFRSG QTCYHPIRGD QLALLGRRTY PRPHEYLSPA DLPKNWDWRNVNGVNYASVT RNQHIPQYCG SCWAHGSTSA MADRINIKRK GAWPSILLSV QNVIDCGNAG SCEGGNDLPVWEYAHKHGIP DETCNNYQAK DQDCDKFNQC GTCTEFKECH TIQNYTLWRV GDYGSLSGREKMMAEIYANG PISCGIMATEMMSNYTGGIY AEHQDQAVIN HIISVAGWGV SNDGIEYWIV RNSWGEPWGE KGWMRIVTST YKGGTGDSYN LAIESACTFGDPIVLEHHHH HH
UniProt Code:Q9WUU7

Cathepsin-Z (CTSZ) is a lysosomal cysteine proteinase and member of the peptidase C1 family. CTSZ, which has been also known as cathepsin X and cathepsin P, exhibits carboxy-monopeptidase and carboxy-dipeptidase activities. CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and, similar to other members of this family, takes part in tumorigenesis.

CTSZ produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 292 amino acids (23-306a.a.) andhaving a molecular mass of 32.8kDa.�(Molecular size on SDS-PAGE will appear atapproximately 28-40kDa).CTSZ is expressed with an 8 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

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