Rat FABP1 Recombinant Protein (RPPB3491)
- SKU:
- RPPB3491
- Product Type:
- Recombinant Protein
- Species:
- Rat
- Uniprot:
- P02692
Description
| Product Name: | Rat FABP1 Recombinant Protein |
| Product Code: | RPPB3491 |
| Size: | 25µg |
| Species: | Rat |
| Target: | FABP1 |
| Synonyms: | Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, p14, Fabp1, Fabplg, FABP1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The FABP1 solution (1mg/1ml) contains phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNFSGKY QVQSQENFEP FMKAMGLPED LIQKGKDIKG VSEIVHEGKK VKLTITYGSK VIHNEFTLGE ECELETMTGE KVKAVVKMEG DNKMVTTFKG IKSVTEFNGD TITNTMTLGD IVYKRVSKRI |
FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallel beta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport and metabolism.
FABP1 Rat Recombinant produced in E. coli is a single non-glycosylated polypeptide chain containing 150 amino acids (1-127) and having a molecular mass of 16.7kDa.FABP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. |
| NCBI Summary: | binds oleic acid and other hydrophobic ligands; may play a role in hepatocyte cell proliferation; may transport activated chemical carcinogens [RGD, Feb 2006] |
| UniProt Code: | P02692 |
| NCBI GenInfo Identifier: | 6978825 |
| NCBI Gene ID: | 24360 |
| NCBI Accession: | NP_036688.1 |
| UniProt Related Accession: | P02692 |
| Molecular Weight: | 14,273 Da |
| NCBI Full Name: | fatty acid-binding protein, liver |
| NCBI Synonym Full Names: | fatty acid binding protein 1 |
| NCBI Official Symbol: | Fabp1�� |
| NCBI Official Synonym Symbols: | SCP; p14; SCP.; Fabplg; L-FABP�� |
| NCBI Protein Information: | fatty acid-binding protein, liver |
| UniProt Protein Name: | Fatty acid-binding protein, liver |
| UniProt Synonym Protein Names: | Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP; Squalene- and sterol-carrier protein; SCP; Z-protein; p14 |
| Protein Family: | Fatty acid-binding protein |
| UniProt Gene Name: | Fabp1�� |
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